What? A Cough Medicine for Depression?

Serotonin antidepressants, step aside there’s a new kid in town. The FDA has just approved a new antidepressant that contains the active ingredient found in over-the-counter cough medicines. This new drug, which will be available soon, is said to work more rapidly than the current antidepressants. So if you’re struggling with depression, this may be something to ask your doctor about in the coming months.


Zorumski, Charles F et al. “Treatment-Resistant Major Depression: Rationale for NMDA Receptors as Targets and Nitrous Oxide as Therapy.” Frontiers in psychiatry vol. 6 172. 9 Dec. 2015, doi: 10.3389/fpsyt.2015.00172

Chandrasekar, Raman. “Alcohol and NMDA receptor: current research and future direction.” Frontiers in molecular neuroscience vol. 6 14. 28 May. 2013, doi: 10.3389/fnmol.2013.00014

Bai G, Hoffman PW. Transcriptional Regulation of NMDA Receptor Expression. In: Van Dongen AM, editor. Biology of the NMDA Receptor. Boca Raton (FL): CRC Press/Taylor & Francis; 2009. Chapter 5.

Mutschler, Jochen et al. “Dextromethorphan withdrawal and dependence syndrome.” Deutsches Arzteblatt international vol. 107,30 (2010): 537-40. doi: 10.3238/arztebl.2010.0537

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